Amy Schumer Showcases Dramatic Weight Loss with Mounjaro in Instagram Post

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Amy Schumer Showcases Dramatic Weight Loss with Mounjaro in Instagram Post

Amy Schumer, the renowned comedian, recently showcased her impressive weight loss transformation in a new Instagram post. On October 4, 2023, Schumer shared a photo from Las Vegas, where she was seen with friends, producer Alex Saks and fellow actress Jillian Bell. The striking image highlighted her new look, featuring a stylish mini dress and heels that displayed her long legs.

Amy Schumer’s Weight Loss Journey

This post garnered significant attention, with many celebrity friends praising her transformation. Notable comments included remarks from Margaret Josephs of The Real Housewives of New Jersey, who emphatically stated, “Ok legs for days!!” Accompanying her comment were fire emojis and a heart, reflecting admiration for Schumer’s figure.

Kathy Griffin, another comedian, expressed playful envy, saying, “I’m so pissed about your legs, I can barely talk to you.”
Schumer responded positively, thanking her supporters with a simple, “Loving the love. My legs thank you!”

Experience with GLP-1 Medications

Amy Schumer has been candid about her experiences with weight-loss treatments. In January 2025, she appeared on Howard Stern’s show, where she disclosed her prior use of Ozempic. However, Schumer experienced severe side effects due to a genetic predisposition to nausea, resulting in debilitating symptoms.

Despite the challenges with Ozempic, Schumer continued her journey with GLP-1 medications. In March 2025, she shared her experience of using Mounjaro, a medication similar to Ozempic, via Instagram. Schumer reported having a positive experience, emphasizing the effectiveness of Mounjaro in her weight-loss efforts.

Openness About Cosmetic Procedures

Amy Schumer is known for her transparency regarding her body image and cosmetic procedures. She previously revealed in a January 2022 Instagram post that she underwent liposuction. This openness resonates with many of her fans, as Schumer continues to navigate her weight-loss journey while sharing her experiences with the public.