New Covid-19 Variant Sparks 15th Wave in France

The emergence of the new Covid-19 variant, known as XFG or “Frankenstein,” has reignited concerns about the virus in France. Recently published data from Santé publique France indicates a moderate circulation of the virus, as cases steadily rise.
Covid-19 Case Surge in France
From September 22 to 28, 2025, the number of Covid-related medical visits showed a significant increase. The data revealed:
- A total of 2,628 respiratory-related medical actions, marking a 15.7% weekly rise.
- Adult cases suspecting infection increased by 16%, adding 313 visits.
- Among children aged 2 to 14, visits also rose by 16% (+47 visits).
These figures have prompted epidemiologist Mircea Sofonea to declare the potential onset of a 15th wave of Covid-19 in France.
Emergency Room Visits Increase
Emergency room visits for potential Covid-19 cases have also surged, particularly among seniors. In patients aged 75 and older, there was a 24% increase, with 30 more visits reported compared to the previous year. However, overall Covid incidence among patients with acute respiratory infections remained stable, indicating a moderate activity level.
The XFG Variant Explained
The new variant, XFG, is a recombination of two previous Omicron strains (LF.7 and LP.8.1.2) and has been under surveillance by the World Health Organization since late June. Health experts confirm that XFG presents a higher transmissibility but no increased severity relative to earlier Omicron variants.
This variant has already been observed in Asia and the United States, corresponding to similar resurgences without significantly impacting healthcare systems. Common symptoms include sore throat and cold-like features.
Upcoming Vaccination Campaign
A new vaccination campaign is set to commence on October 14, 2025, aimed at protecting the elderly and vulnerable populations. The campaign will run until the end of January 2026. Vaccination will be available at no cost, even for individuals not in priority groups.
Health authorities continue to emphasize the importance of vaccination in preventing serious illness and long-Covid complications, particularly for those at higher risk.