Watch Rams vs. 49ers: Channel, Time, Stream for NFL Thursday Night Football

The upcoming clash between the Rams and 49ers marks an exciting moment in NFL Week 5. Both teams, boasting a 3-1 record, vie for the top position in the NFC West. The game will take place on Thursday, October 2, at SoFi Stadium in Los Angeles, kicking off at 8:15 p.m. ET.
Rams vs. 49ers Preview
Los Angeles enters the game following a resounding victory in Week 4. Quarterback Matthew Stafford connected with Tutu Atwell for a memorable 88-yard touchdown. The Rams are healthy and have their top players ready to contribute, including Stafford, Davante Adams, Puka Nacua, and Kyren Williams.
In contrast, San Francisco faces significant injury challenges. Quarterback Brock Purdy and receiver Ricky Pearsall are battling injuries and listed as questionable. Additionally, Jauan Jennings and tight end George Kittle are still sidelined. The performance of star running back Christian McCaffrey will be crucial for the 49ers’ success.
How to Watch Rams vs. 49ers
Fans can catch the Rams vs. 49ers match exclusively on Prime Video. Al Michaels will handle play-by-play duties, with Kirk Herbstreit providing analysis. Kaylee Hartung will report from the sidelines during the game.
Listening Options
Listeners can enjoy live coverage on SiriusXM radio. The Rams broadcast is available on channel 225, while the 49ers broadcast can be found on channel 226. New subscribers to SiriusXM can take advantage of a free first month to access all NFL games and more.
2025 Schedule Highlights
Here’s a snapshot of the upcoming games for both teams:
- Rams 2025 Key Matches:
- Oct. 12 at Ravens – 1 p.m. (FOX)
- Oct. 19 vs. Jaguars – 9:30 a.m. (NFL Network, NFL+)
- 49ers 2025 Key Matches:
- Oct. 12 at Buccaneers – 1 p.m. (CBS)
- Oct. 19 vs. Falcons – 8:20 p.m. (NBC)
As the Rams face off against the 49ers, the stakes are high for both teams. Each victory is critical as they battle for supremacy in the NFC West division.